Arih1全称
Web3 feb 2024 · Cryo-electron microscopy of neddylated SCF-family ligases interacting with the RBR-type E3 ligase ARIH1 reveals the steps through which E3–E3 super-assemblies ubiquitylate a diverse set of ... Web5 mar 2024 · ARIH1 ariadne RBR E3 ubiquitin protein ligase 1. ARIH1. ariadne RBR E3 ubiquitin protein ligase 1. Gene ID: 25820, updated on 5-Mar-2024. Gene type: protein coding. Also known as: ARI; HARI; HHARI; UBCH7BP. See all available tests in GTR for this gene. Go to complete Gene record for ARIH1. Go to Variation Viewer for ARIH1 …
Arih1全称
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Web10 gen 2024 · Complete information for lnc-ARIH1-3 gene (RNA Gene), , including: function, proteins, disorders, pathways, orthologs, and expression. GeneCards - The Human Gene Compendium We’ve updated GeneCards - what’s new in version 5.14 × Web10 ott 2024 · Here, we show that ariadne RBR E3 ubiquitin protein ligase 1 (ARIH1) catalyzes the mono-ISGylation and induces the oligomerization of cGAS, thereby …
Web1 apr 2024 · Ariadne-1 homolog (ARIH1) is a member of the Ariadne family of E3 ubiquitin ligases with many biological functions. ARIH1 is involved in tumorigenesis, cell … Web31 gen 2024 · The epithelial to mesenchymal transition (EMT), a process that is aberrantly activated in cancer and facilitates metastasis to distant organs, requires coordinated transcriptional and post ...
Web19 set 2024 · Because the main known regulators of mitophagy are frequently inactivated in cancer cells, the mechanisms that regulate mitophagy in cancer cells are not fully understood. Here, we identified an E3 ubiquitin ligase (ARIH1/HHARI) that triggers mitophagy in cancer cells in a PINK1-dependent manner. We found that ARIH1/HHARI … WebARIH1 INFORMATION. Proteini. Full gene name according to HGNC. Ariadne RBR E3 ubiquitin protein ligase 1. Gene namei. Official gene symbol, which is typically a short form of the gene name, according to HGNC. ARIH1 (ARI, HARI, HHARI, UBCH7BP) Protein classi. Assigned HPA protein class (es) for the encoded protein (s).
WebARIH1 Antibody (C-7) is an IgG 2b κ mouse monoclonal ARIH1 antibody (also designated ARIH1 antibody) that detects the ARIH1 protein of mouse, rat and human origin by WB, …
Web21 apr 2024 · 4t1是一种小鼠乳腺癌细胞，实验表明，arih1过表达的4t1细胞接种至免疫系统缺陷的裸鼠体内后，其生长和增殖速度与野生型4t1细胞无异；然而接种至野生型小鼠乳 … richest temple in karnatakaWebARIH1 Expression Promotes Elimination of Depolarized Mitochondria Parkin is a member of the RBR family of E3 ligases that is composed of 14 complex multidomain enzymes. As it is frequently downregulated in cancer cells, we investigated whether other E3 ligases could control mitophagy in these cells. richest tennis players 2016Web10 ott 2024 · ARIH1 is a component of the CRL system and regulates cancer progression and xenophagy of cytosolic bacteria 46, 49, 50, 51. Since ARIH1 interacts with cGAS … red painted poolsWeb18 ago 2024 · ubiquitination: ARIH1 enters the fray. Ubiquitination is a post-translational modification in which ubiquitin, a 76-amino acid polypeptide, is covalently bound to one or more lysines of a target protein. Ubiquitination is mediated by the coordinated activity of ubiquitin activating (E1), conjugating (E2), and ligating (E3) enzymes. red painted pineconesred painted glassWebMembers of the RBR family are atypical E3 ligases. They interact with the E2 conjugating enzyme UBE2L3 and function like HECT-type E3 enzymes: they bind E2s via the first RING-type zinc finger, but require an obligate trans-thiolation step during the ubiquitin transfer, requiring a conserved active site Cys residue in the second RING-type zinc finger … red painted roadWebThe E3-E3 mechanism places the ubiquitin-linked active site of ARIH1 adjacent to substrates bound to F-box proteins (for example, substrates with folded structures or limited length) that are incompatible with previously described conventional RING E3-only mechanisms. The versatile E3-E3 super-assembly may therefore underlie widespread ... richest ten percent controlled perhaps